Sunday, December 29, 2019

The Social Life Of Megan Meier - 1533 Words

CHAPTER I Introduction Megan Meier was a regular teenager who enjoyed all types of leisure activities, such as fishing with her father, playing volleyball, watching horror films, including helping her friends out and playing with her dog. Unfortunately, society has pressured woman regarding body standards and their desperation of trying to look â€Å"less fat†. Thus, Megan had weight issues and this slowly caused her depression and her self-esteem dropped drastically. Her parents relocated her to a private school when she was in eighth grade, which was a significant good decision for them as she started to feel more confident in her skin. At the age of fourteen, Megan requested to her parents a MySpace account. Her parents granted her request, along with several restrictions for her such as approving her page content, letting them know her password, being present in her room while she was online, and setting her profile to private. Moreover, Megan slowly started to develop an online social life. This was very common in the teenage era. In September 2006, Megan received an unusual request from a stranger. His name was Josh Evans. By looking at his profile, it seemed that he was an attractive, decent-looking, young boy with no intended harm. Her mom, Tina, wasn’t sure about this, but following with some unwillingness uncertainty, she granted Megan permission to accept Josh’s request. Furthermore, Megan’s relationship with Josh made her attitude change from dull and grey toShow MoreRelatedTelevisions Effect On Society1475 Words   |  6 Pagesconsider to be fundamental. Voters and officials alike must pay attention to the media. Television has significant effect on our general public. It has changed the ways of life of the general population and has turned into a noteworthy impact in our way of life. Not at all like printing, which took many years to impact the way of life, TV s effect was practically quick. Television has involved an imperative position in homes and therefore, it is certain to have an effect on the people and the generalRead MoreCyber Bullying Essay example1112 Words   |  5 PagesSocial Networking has taken bullying to the extreme. Before advanced technology, children and teenagers were troubled by school bullies. Today, they are targeted by bullies via internet. Most people undergo some form of bullying in life. Growing up, I experienced the typical name calling and spiteful comments. I also dealt with minor cases of virtual bullies. These bullies are known as cyber bullies. I find this topic compelling because it’s a matter that has spiraled out of control. â€Å"Cyber bullyingRead MoreArgumentative Essay932 Words   |  4 Pagesï » ¿Argumentative Essay Braden Rawson Social Networking or the use of specific websites or applications to interact with other users is one of the many key and driving factors today in our world. We find ourselves lost for many minutes or possibly hours at a time on any particular app or website. Looking deeper into the issue of social networking and its impact on our life, I highly doubt we have accomplished anything at all. A very smart man once said, â€Å"Time is money.† If that quote is true do weRead MoreNegative Effects Of Cyber Bullying1528 Words   |  7 PagesBullying in America Today|NoBullying|, 2015). What do you think a preteen is going to do when there is no supervision while online? They are going to test their limits, go on sites they shouldn’t and that leads to going to chats, Facebook or any other social media sites, and maybe one day a particular student got into an argument with a classmate, see that they are also online and gets angry and starts saying mean things, then it escalates, and who knows where it ends, above all parents need to monitorRead MoreBullying Awareness Programs Should Be Beneficial1148 Words   |  5 Pagesfacing the ordeal of bullying. For example, a girl named Megan Taylor Meier who was an American teenager from Dardenne Prairie, Missouri committed suicide by hanging herself three weeks before her 14th birthday on October 17, 2006. One year after her death, Megan’s parents started an investigation and learned that their daughters’ suicide attributed due to cyber bullying through the social networking site MySpace. Megan had been under the care of a psychiatrist since the third grade, andRead MoreEssay on The Growing Epidemic of Cyberbullying1121 Words   |  5 Pageshas gotten so dangerous that children have killed each other and/or committed suicide after having been involved in a cyber bullying incident. Little attention and support from school authorities, more access to computers, and the latest cool thing (social networks) are all factors that have contributed to the rising of cyber-bullying practices. Cyber bullying is when a preteen or teen is harassed, threatened, humiliated, embarrassed or otherwise molested by another child with the useRead MoreTaking a Look at Bullying676 Words   |  3 Pagessomeone raise their confidence, the victim is helpless and insecure so this problem needs to be stopped as a result, the possible victims can feel safe and protected out in the public. Bullies can come in all different sizes and shapes, having a hard life at home can be a reason why bullies bully other reasons can be because they just like to pick on people. A bully can result from being raised in a family that does not have any morals or any structures. Spanking, hitting, shoving and other forms ofRead MoreBullies Need a Harsher Punishment1538 Words   |  7 Pageswere ignored. Teen Suicide Cases Phoebe Prince was not just an immigrant girl; she was a beautiful 15-year-old girl who moved to South Hadley, M.A. from a small village in western Ireland. Like many teenage girls driven by a technological social life, Phoebe created a profile on a popular networking site. Unbeknownst to her, trying to fit in would ultimately rear its ugly head. As a freshman, she dated Sean Mulveyhill, but after their breakup, he and four other persons began to harass PhoebeRead MoreCyberbullying: an Issue Beyond Adolescence Essay4085 Words   |  17 Pagesas describe several case studies that reflect the results of being victimized. These studies are represented by research conducted by accredited sources. Within this research paper, we will talk about the life of four young adolescents who were taunted, bullied, humiliated, and harassed via social media and the decisions they made. This research paper discusses that cyberbullying is a problem beyond childhood and adolescence and will provide possible solutions taking into account that although thereRead MoreTaking a Look at Cyberbullying1105 Words   |  4 PagesIn May 2013, Gabrielle Molina, a 12 year old excellent and outwardly positive student, took her life after being called a â€Å"slut† and a â€Å"whore† online. Throughout the use of social media, teens are potentially susceptible to become victims of cyber-bullying, and the drama that rises from it could work as a catalyst in the development of psychological traumas. To help the prevention of bullying, parents and schools must work hand in hand in this issue by incorporating anti-bullying education in their

Friday, December 20, 2019

Effective Gene Delivery And Its Effects On Hiv - 987 Words

There has been countless number of efforts to develop an effective gene transfer approach to treat HIV-1 infections globally. Many transgenes have been identified to inhibit in vitro HIV-1 infections. As drug resistant HIV-1 is increasingly common even with patients receiving HAART, designing drug treatment methods have been challenging. Therefore, investigation into new therapeutic approaches should continue. Gene delivery plays an important supporting role developing potential therapies directed towards HIV-1 infections. The goals of the anti-HIV-1 gene therapy are to deliver transgenes to directly susceptible cells, Immunize against HIV-1 antigens, inhibit HIV-1 proliferation in target organs, and deliver to Hematopoietic Progenitor Cells. Delivering transgenes to susceptible cells will make them resistant to HIV-1 infections and inhibit viral replication. When CCR5 a major coreceptor for HIV was disrupted in the â€Å"Berlin Patient† led to the revival of gene therapy . The naturally occurring CCR5-Δ32 mutation that results in a frameshift mutation dislocates the CCR5 expression on the cell surface. The â€Å"Berlin patient† who was HIV+ patient with lymphoma was transplanted with bone marrow from a donor with CCR5-Δ32 mutation and became ‘cured’ of HIV. But as only a small general population with CCR5-Δ32 mutation can be identified alternative methods must be identified for gene therapy. Though gene therapies for HIV-1 infections have been challenging recent work must beShow MoreRelatedThat Target The Gene Codes For A Protein Found On The Surface Of White Blood Cells1671 Words   |  7 PagesZFNs that Target the Gene CCR5 The CCR5 gene codes for a protein found on the surface of white blood cells that acts as a receptor for chemokines. The HIV virus, strain R5-tropic virus, initially uses the CCR5 chemokine receptor to attach to the CD4+ helper T-cells. The Berlin patient showed how a CCR5-negative hematopoietic stem/ progenitor cells (HSC) from a CCR5 ∆ 32 donor can be used to generate HIV-1 resistant CD4+ helper T-cells.3 Mice models using in vivo studies have also shown ZFNs to beRead MoreUseful Medicinal Compounds Derived from Animals632 Words   |  3 Pagesimmune system can recognize. Finally, immune response will be triggered. Tumor cell can be killed by B-cell or Phagocyte. Over a hundred years ago, target drug idea has been proposed. If a drug can be delivery to the target site precisely, the adverse effect of the drug can be minimized. â€Å"Delivery the drug to the target site† became a challenge the scientist. In the 1970s, B-cell has been discovered and played essential role (Biotech Resources, 1995-7). Anyways, as the technology, antibody cannotRead MoreFoamy Virus Case Study1329 Words   |  6 Pages2017) The foamy viral primer, central polypurine tract(cPPT) produced gap in double stranded viral DNA of 144 to 731 bp. The 3 and 5’ terminus of the cleavage is located between 6272-6274 bp and 465 bp range respectively. Mutation of fourth cPPT and HIV-1 virus resulted in a substantial attenuation of foamy virion indicates the indispensability of cPPT for viral DNA synthesis. (Chen et al., 2017) Cytotoxicity and multiple transduction rounds of current viral vectors necessitate the foamy virus vectorRead MoreThe Usefulness Of Viral Vectors1223 Words   |  5 PagesVoltage-gated sodium channels initiate the development action potentials in neurons; mutations of genes encoding these channels are responsible for genetic epilepsy syndromes with varying degrees of severity1. Dravet syndrome, or severe myoclonic epilepsy of infancy (SMEI), is a complex and severe form of childhood epilepsy, caused by a nonsense mutation in the sodium voltage-gated channel alpha subunit 1 (SCN1a) gene. Severe loss of function mutation in Nav1.1 causes SMEI, which involves intractable epilepsyRead MoreNanoparticles : HIV And The Human Immunodeficiency Virus1085 Words   |  5 Pagesin targeted drug delivery while minimizing toxicity. Gold is used as the basis for nanoparticles because it has a relatively high stability of ligand binding along with its decreased stability with other cells. Gold nan oparticles (AuNPs) also have a high concentration of glutathione, which is an antioxidant that prevents damage to cells from things like free radicals and peroxides. We are using AuNPs to carry drugs to cells infected with the Human Immunodeficiency Virus (HIV). HIV is a virus in theRead MoreGene Silencing : Current Approaches And Relevance For Drug Discovery2632 Words   |  11 PagesTITLE: Gene Silencing – Current Approaches and Relevance for Drug Discovery NEW TITLE: OUTLINE: Abstract Gene silencing is an evolving field that holds great promise for personalized drug discovery. The ability to interfere with mutated genes gives rise to the possibility of shutting down disease causing mechanisms and the advent of personalized drugs for specific diseases. The prospect of easily silencing genes in the lab for functional genomic studies has not fully crossed over into theRead MoreGlucagon Like Peptide-1 Essay791 Words   |  4 Pageseating. GLP-1 has many beneficial effects in diabetes including (but not limited to) activation of somatostatin secretion from delta cells, inhibition of glucagon release from alpha cells, reduced gastric emptying, and food intake resulting in weight loss in the long run. Unfortunately, the incretin response to glucose is reduced in type 2 diabetes (T2DM) accompanied by a moderate degree of GLP-1 hypo-secretion. To compensate the reduced incretin effect, we generated an HIV-based lentiviral vector to deliverRead MoreGene Therapy And Its Effects1619 Words   |  7 Pagespatients are treated. Recently, gene therapy has been propelled into the spotlight with the most recent successful clinical trial in which scientists reprogrammed ordinary cardiac cells in pigs to mirror the function of the sinoatrial node, thereby inducing a steady heartbeat. In the last few decades since its inception, gene therapy has rapidly advanced; there have been remarkable strides in its methods and an increase in the range of targetable diseases. Gene therapy is the modification of theRead MoreCase Study : Rna Interference : What Advances Have Been Made From The Last Decade?1435 Words   |  6 Pages................................................................ 8 Delivery ...................................................................................................................................................................8 Stability ...................................................................................................................................................................9 Off-Target Effect...................................................................Read MoreEssay about Priotities of Gene Therapy2802 Words   |  12 PagesPriotities of Gene Therapy Gene therapy is a relatively new area of medicine that attempts to apply recent advances in molecular biology, genetics and biotechnology to the treatment of human diseases. Gene therapy uses a set of approaches to the treatment of human disease based on the transfer of genetic material (DNA) into an individual. Gene delivery can be achieved either by direct administration of gene-containing viruses or DNA to blood or tissues, or indirectly through the introduction

Thursday, December 12, 2019

Taxation Law Transactions Incurred by Mandy Morris†Free Samples

Question: What are the Australian tax consequences of these transactions for Mandy Morris,Explain and justify your answer relevant case laws? Answer: The following case study is based on the determination of tax consequences of transactions incurred by Mandy Morris. An individual leasing the commercial premises to others must include the full amount of rental income derived from such leasing in their income tax return. As evident from the existing situation, Mandy had derived rental income of $10,000 from the commercial leasing of her Australian home. The second point to be considered in context of rental income states that ordinarily where the taxpayer grants the property on lease or license it whether wholly or partially, the amount derived in the form of rent by Mandy will be considered in the assessable income (Barkoczy 2016). Referring to the illustrations made under FCT v Kowal, 84 ATC 4001, the money derived by Mandy will be regarded as assessable income. Dividends that are paid to the shareholders by the Australian resident companies are held for taxation under the system that is known as imputation (Woellner et al. 2013). Mandy had borrowed from the Westpac Bank to purchase shares in Worldwide Australia Ltd and received $2,500 fully franked distribution, which is subjected to tax under the imputation system. Therefore, Mandy had received dividends from the Australian resident company and it will tax under the imputation system. An individual can claim deduction upon the interest that is charged on money borrowed to purchase shares. Mandy can claim a deduction on interest charged by the bank on money that is borrowed from the Westpac to purchase shares. References Barkoczy, S., 2016. Foundations of Taxation Law 2016.OUP Catalogue. Woellner, R., Barkoczy, S., Murphy, S., Evans, C. and Pinto, D., 2013.Australian Taxation Law Select: legislation and commentary. CCH Australia.